Emergency Medicine Journal – Narrative Case Series Presentation It was a Tuesday afternoon in a busy UK district general hospital. The department was in its usual post-lunch chaos when triage flagged a 58-year-old man, Mr. Patel, as “priority 2 – possible stroke.” The paramedic handover was clipped: “Found by his wife at home, last known well 45 minutes ago. Sudden right-sided weakness, slurred speech, and facial droop. GCS 14. BP 185/100, HR 88, SpO₂ 97% on air. Blood glucose 6.2 mmol/L.”
The clock started. Dr. James Cooper, the emergency medicine registrar, met the patient in Resus 4. Mr. Patel was awake but unable to raise his right arm or leg. His speech was dense, global aphasia – not just slurred, but absent. He followed left-sided commands with his eyes. The face showed a pronounced right lower facial droop. emergency medicine journal
“Status epilepticus? Or stroke progression?” James murmured. He gave 2 mg IV lorazepam. The jerking stopped, but the aphasia and hemiparesis remained unchanged. Blood glucose 6
The stroke consultant, Dr. Khan, arrived. “This is a large vessel occlusion. Thrombolysis alone may not recanalise. We need mechanical thrombectomy, but our nearest centre is 45 minutes away by ambulance.” and he was unresponsive.
Meanwhile, the nurse recorded a blood pressure of 205/110. James recalled the 2024 EMJ guidelines: BP >185/110 is a relative contraindication to IV alteplase unless rapidly controlled. He ordered IV labetalol 10 mg push. As the labetalol took effect (BP 168/94), Mr. Patel suddenly became agitated. His left arm began jerking rhythmically. The monitor showed tachycardia to 120. Junior doctor Sarah shouted, “Seizure?” James shook his head – the movements were focal, but the patient’s eyes were deviated to the left, and he was unresponsive.